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Exam Code: A00-282
Exam Name: Clinical Trials Programming Using SAS 9.4
Updated: Aug 27, 2026
Q & A: 144 Questions and Answers
A00-282 Free Demo download
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| Section | Weight | Objectives |
|---|---|---|
| Transform or Summarize Clinical Trials Data | 15% | - Derive variables and study days - Aggregation and transposition - Data step manipulation |
| Regulatory Submissions | 5% | - Compliance for clinical data reporting - ICH and FDA guidelines |
| Report Clinical Trials Results | 10% | - Produce tables, listings, and figures - PROC REPORT and PROC PRINT |
| Macro Programming for Clinical Trials | 15% | - Create and call macros - Macro variables and parameters - Debugging macros |
| Clinical Trials Process | 5% | - Derive programming requirements from protocol and CRF - Clinical trial lifecycle and protocol |
| Validate Clinical Trial Data Reporting | 20% | - Programming validation techniques - Validation principles - Use PROC COMPARE and log review |
| Manage Clinical Trials Data | 5% | - Access and explore clinical datasets - Clean, merge, and subset data - Use SQL and dictionary tables |
| Apply Statistical Procedures for Clinical Trials | 15% | - PROC MEANS, FREQ, TABULATE - Basic statistical analysis for clinical data |
| Clinical Trials Data Structures | 10% | - Clinical domain structures - CDISC standards: SDTM, ADaM - Define.xml and dataset specifications |
Question 1
This question will ask you to provide a line of missing code.
Which line of code would produce the blue notes in the log?
A. if indm ne indisp then put 'MERGE ISSUE: ' subjid= indm= indisp=;
B. %if indm ne indisp %then %put 'MERGE ISSUE: ' subjid= indm= indisp=;
C. if indm ne indisp then put 'MERGE ISSUE: ' _all_;
D. if indm ne indisp then output 'MERGE ISSUE: ' subjid indm indisp;
Question 2
This question will ask you to provide a line of missing code. Given the data set RAWBP that is sorted by SUBJECT TEST WEEK:
The following SAS program is submitted:
data bp;
set rawbp;
by subject test week;
retain baseline;
if first.test then baseline = .;
if week = 0 then baseline = value;
else if week > 0 then do;
<insert code here>
end;
run;
Which statement must be added to the program to calculate percent change from baseline?
A. pct_chg = ((baseline - value) /baseline)*100;
B. pct_chg = ((value - baseline) /baseline)*100;
C. pct_chg = ((baseline - value) /value)*100;
D. pct_chg = ((value - baseline) /value)*100;
Question 3
What is an international ethical and scientific quality standard for designing, conducting, recording and reporting trials that involve the participation of human subjects
A. Good Clinical Practices
B. WHODrug
C. MedDRA
D. 21 CFR Part 11
Question 4
Which COMPUTE block correctly completes the code shown below to compute the ratio of the median Length to the median Weight?
proc report data = DM;
columns USUBJID Ratio Length Weight;
define USUBJID / group;
define Ratio / computed;
define Length / analysis median;
define Weight / analysis median;
run;
A. compute Ratio;
Ratio = Length.Median / Weight.Median;
endcomp;
B. compute Weight;
Ratio = Length.Median / Weight.Median;
endcomp;
C. compute Ratio;
Ratio = Length/ Weight;
endcomp;
D. compute Weight;
Ratio = Length / Weight;
endcomp;
Question 5
Identify the CDISC model with the following characteristics:
XML-based content and format standard facilitates the archive and interchange of the metadata and data for clinical research provides an accurate audit trail that is 21 CRF Part II compliant
A. Analysis Data Model (ADaM)
B. Operational Data Model (ODM)
C. Trial Design Model (TDM)
D. Study Data Tabulation Model (SDTM)
Solutions:
| Question 1 Answer: A | Question 2 Answer: B | Question 3 Answer: A | Question 4 Answer: D | Question 5 Answer: B |
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