SASInstitute A00-282 : Clinical Trials Programming Using SAS 9.4

A00-282 real exams

Exam Code: A00-282

Exam Name: Clinical Trials Programming Using SAS 9.4

Updated: Aug 27, 2026

Q & A: 144 Questions and Answers

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SASInstitute A00-282 Exam Syllabus Topics:

SectionWeightObjectives
Transform or Summarize Clinical Trials Data15%- Derive variables and study days
- Aggregation and transposition
- Data step manipulation
Regulatory Submissions5%- Compliance for clinical data reporting
- ICH and FDA guidelines
Report Clinical Trials Results10%- Produce tables, listings, and figures
- PROC REPORT and PROC PRINT
Macro Programming for Clinical Trials15%- Create and call macros
- Macro variables and parameters
- Debugging macros
Clinical Trials Process5%- Derive programming requirements from protocol and CRF
- Clinical trial lifecycle and protocol
Validate Clinical Trial Data Reporting20%- Programming validation techniques
- Validation principles
- Use PROC COMPARE and log review
Manage Clinical Trials Data5%- Access and explore clinical datasets
- Clean, merge, and subset data
- Use SQL and dictionary tables
Apply Statistical Procedures for Clinical Trials15%- PROC MEANS, FREQ, TABULATE
- Basic statistical analysis for clinical data
Clinical Trials Data Structures10%- Clinical domain structures
- CDISC standards: SDTM, ADaM
- Define.xml and dataset specifications

SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

Question 1

This question will ask you to provide a line of missing code.

Which line of code would produce the blue notes in the log?

A. if indm ne indisp then put 'MERGE ISSUE: ' subjid= indm= indisp=;
B. %if indm ne indisp %then %put 'MERGE ISSUE: ' subjid= indm= indisp=;
C. if indm ne indisp then put 'MERGE ISSUE: ' _all_;
D. if indm ne indisp then output 'MERGE ISSUE: ' subjid indm indisp;


Question 2

This question will ask you to provide a line of missing code. Given the data set RAWBP that is sorted by SUBJECT TEST WEEK:

The following SAS program is submitted:
data bp;
set rawbp;
by subject test week;
retain baseline;
if first.test then baseline = .;
if week = 0 then baseline = value;
else if week > 0 then do;
<insert code here>
end;
run;
Which statement must be added to the program to calculate percent change from baseline?

A. pct_chg = ((baseline - value) /baseline)*100;
B. pct_chg = ((value - baseline) /baseline)*100;
C. pct_chg = ((baseline - value) /value)*100;
D. pct_chg = ((value - baseline) /value)*100;


Question 3

What is an international ethical and scientific quality standard for designing, conducting, recording and reporting trials that involve the participation of human subjects

A. Good Clinical Practices
B. WHODrug
C. MedDRA
D. 21 CFR Part 11


Question 4

Which COMPUTE block correctly completes the code shown below to compute the ratio of the median Length to the median Weight?
proc report data = DM;
columns USUBJID Ratio Length Weight;
define USUBJID / group;
define Ratio / computed;
define Length / analysis median;
define Weight / analysis median;
run;

A. compute Ratio;
Ratio = Length.Median / Weight.Median;
endcomp;
B. compute Weight;
Ratio = Length.Median / Weight.Median;
endcomp;
C. compute Ratio;
Ratio = Length/ Weight;
endcomp;
D. compute Weight;
Ratio = Length / Weight;
endcomp;


Question 5

Identify the CDISC model with the following characteristics:
XML-based content and format standard facilitates the archive and interchange of the metadata and data for clinical research provides an accurate audit trail that is 21 CRF Part II compliant

A. Analysis Data Model (ADaM)
B. Operational Data Model (ODM)
C. Trial Design Model (TDM)
D. Study Data Tabulation Model (SDTM)


Solutions:

Question 1
Answer: A
Question 2
Answer: B
Question 3
Answer: A
Question 4
Answer: D
Question 5
Answer: B

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